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BIOLOGICAL SYSTEMS: Amblard, François Telephone : 052-217-5523

  • Profile
    * Academic background
     
    High-level maths classes, Louis le Grand College, Paris.
    1982-85: Ecole Polytechnique : major in  maths and physics.
    1985-86 : Master degree in Biochemistry, Master degree in Cell and Molecular Biology.
    1985-86: 18 months research work in neurobiology  (Collège de France, Prof. Alain Prochiantz).
    1985-91: PhD, Collège de France, with Prof. Alain Fischer (pediatric immunology) & Dr. Charles Auffray (genetics). "Molecular and physical bases of intercellular adhesion during antigen recognition"
    expertise gained in : biochemistry, molecular biology, cellular immunology, microhydrodynamics.
     
    * Professional appointments
     
    1991-92: Post-doctoral researcher : immunogenetics,  Weizmann fellow at the Pasteur Institute, Paris.
    1992-93: Head of a 6-people research team. prenatal diagnosis biotech startup, Paris.
    1993-95: Post-doctoral fellow. Princeton University, dept. of Physics, and dept. of Molecular Biology.
    Prof. Stanislas Leibler, Princeton and Dr. Bernie Yurke, Bells Labs. expertise gained in : microrheology, magnetism, electronics, polymer theory.
    Since 1995 : permanent CNRS position : obtained in the Laboratory of Theoretical Physics, ESPCI, Paris.
    Since 1998 : CNRS researcher : the Curie Institute, Physics dept. since 2000 : group leader.   since 2004 : research director.
    2003 : Team member for the foundation of the french national MD-PhD programme.
    in charge of the Physics education and mentoring ever since. 
    2007 : Start of the MD-PhD programme at Paris-Descartes university (leading french medical-school).
    in charge of the Physics education ever since.
     
    * Research interests since 1995 :
     
    Physics:     
    Microrheology, non-equilibrium polymer dynamics, multiple light scattering, microscopic heat transfers and ultrafast thermal detection.
     
    Biochemistry & self-assembly :
    actin polymerization, biochemistry in two dimensions,
    kinetic control of self-assembly, polymer crystallization, theory.

    Cell biology and  multicellular assemblies:
    cytoskeleton dynamics,
    dynamic control of cell functions : instability-driven motility, dynamic stabilization of epithelia, social control of phenotype diversity and stability, nucleation of the oncogenic process.
     
    Instrumentation:
    non-linear optical microscopy, (I initiated it in France, starting in 1997)
    optical cell biology methods: FRAP, ablation, microfabrication, optical gene induction.
     
  • Group achievements
  • Group research

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